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갑상선 결절의 분자생물학적 진단

Title
갑상선 결절의 분자생물학적 진단
Other Titles
Molecular Diagnosis of Thyroid Nodule
Author
지용배
Keywords
Diagnosis; Genetic testing; Molecular diagnostic techniques; Thyroid carcinoma; Thyroid nodule
Issue Date
2018-09
Publisher
대한이비인후과학회
Citation
대한이비인후과학회지 두경부외과학, v. 61, no. 9, page. 445-452
Abstract
Fine needle aspiration cytology is gold standard for diagnosis of thyroid nodule. However, it isnot perfect and its results are cytologically indeterminate nodules (Bethesda classification IIIV)in 15-30%, which remains diagnostic challenges. So, the method that provide informationabout cancer risk is necessary to establish management strategy. As results of studies aboutgenetic changes in thyroid cancer, remarkable advances have been achieved in understandingthyroid carcinogenesis, which produced applications of molecular biomarkers and profilingpanels for diagnosis of thyroid nodule. These tests help clinicians make decision regarding theneed for surgery and the surgical extent. In this review, published researches related to moleculardiagnosis of thyroid cancer are reviewed and performance of the diagnostic tests and itsinterpretation were discussed. Korean J Otorhinolaryngol-Head Neck Surg 2018;61(9):445-52
URI
http://kjorl.org/journal/view.php?doi=10.3342/kjorl-hns.2018.00493http://repository.hanyang.ac.kr/handle/20.500.11754/120035
ISSN
2092-6529; 2092-5859
DOI
10.3342/kjorl-hns.2018.00493
Appears in Collections:
COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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