10 2

Changes in lipid indices and body composition one year after laparoscopic gastrectomy: a prospective study

Title
Changes in lipid indices and body composition one year after laparoscopic gastrectomy: a prospective study
Author
하태경
Keywords
Lipids; Body composition; Weight loss; Gastrectomy
Issue Date
2018-05
Publisher
BIOMED CENTRAL LTD
Citation
LIPIDS IN HEALTH AND DISEASE, v. 17, Article no. 113
Abstract
Background: The purpose of this prospective study was to investigate changes in lipid indices associated with whole body composition during 1 year of follow-up after laparoscopic gastrectomy.Methods: Thirty-seven patients with benign and malignant gastric neoplasm who underwent laparoscopic gastrectomy were prospectively enrolled. None of the patients were treated with adjuvant chemotherapy. Lipid indices and body composition were measured preoperatively and at six and 12 months after laparoscopic gastrectomy. Lipid indices included total cholesterol (TC), triglyceride (TG), low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (HDL-C). Body weight fat and lean body mass (LBM) were measured by dual-energy X-ray absorptiometry and the change in fat and LBM in the trunk, arms and legs was compared.Results: Body weight significantly decreased from 63.0 +/- 11.1 kg preoperatively to 56.8 +/- 10.6 kg 12 months after laparoscopic gastrectomy, with a mean of 7.1% (4.6 kg) weight loss. Fat and LBM loss contributed 68.4% (3.1 kg) and 30.1% (1.4 kg) of the total weight loss, respectively. In both the non-obese and obese groups, body weight, fat and LBM did not change significantly between 6 months and 12 months after gastrectomy. TC and LDL-C levels significantly decreased during the first six-month period and HDL-C significantly increased until 12 months after gastrectomy in the non-obese group. In the obese group, the degree of reduction in fat mass was significantly higher and the LBM/weight ratio significantly increased compared with the non-obese group. However, there was no significant change in lipid indices in the obese group. The TG level was significantly correlated with fat especially with trunk fat.Conclusion: Gastrectomy resulted in improved lipid indices and a reduction in body weight fat and LBM. The HDL-C significantly increased in the non-obese group for 1 year after gastrectomy and the reduction of TG level was positively correlated with fat, especially with trunk fat (IRB No. 2015-04-026. Registered 4 May 2015).
URI
https://lipidworld.biomedcentral.com/articles/10.1186/s12944-018-0729-1http://repository.hanyang.ac.kr/handle/20.500.11754/118667
ISSN
1476-511X
DOI
10.1186/s12944-018-0729-1
Appears in Collections:
COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
Files in This Item:
Changes in lipid indices and body composition one year after laparoscopic gastrectomy a prospective study.pdfDownload
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE