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Effectiveness of proton pump inhibitor for the treatment of contact granuloma

Title
Effectiveness of proton pump inhibitor for the treatment of contact granuloma
Other Titles
접촉성 육아종에서 양성자 펌프 억제제의 치료 효과
Author
송창면
Keywords
접촉성 육아종; 양성자 펌프 억제제; 인후두 역류; 위식도 역류; Contact granuloma; Proton pump inhibitor; Laryngopharyngeal reflux; Gastroesophageal reflux
Issue Date
2017-12
Publisher
대한후두음성언어의학회
Citation
대한후두음성언어의학회지, v. 28, no. 2, page. 123-127
Abstract
Background and Objectives Contact granuloma is granulation tissue that occurs mainly in the vocal process of arytenoid cartilage. Among several etiological factors, gastric acid reflux is known to be an important cause. The aim of this study was to evaluate clinical characteristics of contact granuloma and analyze the effectiveness of proton pump inhibitor in the treatment of contact granuloma.Materials and Methods We retrospectively reviewed the medical records of 40 patients who were treated with proton pump inhibitor (PPI) for contact granuloma from January 2011 to December 2015. Reflux finding score (RFS), reflux symptom index (RSI) and size of granuloma were evaluated before and after treatment serially to assess the effectiveness of proton pump inhibitor.Results Of 40 patients, 25 patients (62.5%) and 10 patients (25%) showed improvement and partial improvement of granuloma, respectively. Five patients showed no response. The mean times of partial improvement and improvement were 2.08±2.23 months and 4.60±2.77 months, respectively and mean duration of PPI treatment was 6.8±5.2 months.Conclusion Proton pump inhibitors is effective in the treatment of contact granuloma.
URI
https://jkslp.org/journal/view.php?doi=10.22469/jkslp.2017.28.2.123http://repository.hanyang.ac.kr/handle/20.500.11754/116542
ISSN
2508-268X; 2508-5603
DOI
10.22469/jkslp.2017.28.2.123
Appears in Collections:
COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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