Background and Objectives：The management of Reinke’s edema includes usually medical treatment and voice therapy. Laryngomicrosurgery (LMS) is also necessary, especially to improve airway obstruction. However, voice outcome after LMS has not been determined well. The aim of this study was to evaluate effectiveness of LMS for Reinke’s edema and analyze the voice outcomes after LMS. Materials and Methods：Twenty-five patients with Reinke’s edema who underwent LMS from September 2007 to December 2016 were enrolled in this study. We analyzed reflux finding score (RFS), reflux symptom index (RSI), and acoustic parameters before and after surgery. Results：Male was 15 (60%) and female was 10 (40%), and mean age was 49.6 years. Preoperative mean value of RFS decreased significantly up to 3 months after LMS (18.3±2.2 and 10.0±2.2 at preoperative and 3 months postoperatively, respectively). The mean value of Jitter decreased significantly before and after surgery (2.71±2.81% and 1.06±1.21% before and after LMS, p=0.041). The mean value of Shimmer also decreased significantly before and after surgery (7.97±3.63% and 4.83±1.85%, respectively, p=0.006). Conclusion：LMS is effective in the treatment of Reinke’s edema. It results in favorable acoustic outcomes and laryngoscopic findings in properly selected patients.