Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 전대원 | - |
dc.date.accessioned | 2019-12-02T02:34:32Z | - |
dc.date.available | 2019-12-02T02:34:32Z | - |
dc.date.issued | 2017-11 | - |
dc.identifier.citation | GUT AND LIVER, v. 11, no. 6, page. 852-859 | en_US |
dc.identifier.issn | 1976-2283 | - |
dc.identifier.issn | 2005-1212 | - |
dc.identifier.uri | http://www.gutnliver.org/journal/view.html?doi=10.5009/gnl16521 | - |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/116227 | - |
dc.description.abstract | Background/Aims: To investigate the use of measurements of liver stiffness (LS) by two-dimensional real-time shear wave elastography (SWE) for predicting the development of hepatocellular carcinoma (HCC) in patients with chronic hepatitis B (CHB). Methods: We retrospectively collected data on 291 enrolled patients with CHB whose LS had been measured using SWE. Results: The mean age of the patients was 46.8 years; males predominated (67%), and 40 of the patients (14%) had clinical cirrhosis. Among the patients, 165 (56.7%) received antiviral treatment. The median LS value was 7.4 kPa, and the median follow-up period was 35.8 months (range, 3.0 to 52.8 months). During follow-up, HCC developed in 13 patients (4.5%), and the cumulative incidence rates of HCC at 1, 2, and 4 years were 1.1%, 3.6%, and 8.4%, respectively. Based on a multivariate analysis, older age (>= 50 years) and higher LS value (>= 10 kPa) were independently associated with the risk of developing HCC (hazard ratio [HR], 4.53, p=0.023; and HR, 4.08, p=0.022). The cumulative incidence rate of HCC was significantly higher in patients with higher LS values (>= 10 kPa) than in those with lower LS values (< 10 kPa) (p=0.001). Conclusions: Increased LS measured by SWE at any time point regardless of antiviral treatment is associated with an increased risk of HCC in patients with CHB. | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | EDITORIAL OFFICE GUT & LIVER | en_US |
dc.subject | Elastography | en_US |
dc.subject | shear wave | en_US |
dc.subject | Liver stiffness | en_US |
dc.subject | Hepatitis B | en_US |
dc.subject | chronic | en_US |
dc.subject | Carcinoma | en_US |
dc.subject | hepatocellular | en_US |
dc.title | Role of Shear Wave Elastography in Evaluating the Risk of Hepatocellular Carcinoma in Patients with Chronic Hepatitis B | en_US |
dc.type | Article | en_US |
dc.relation.no | 6 | - |
dc.relation.volume | 11 | - |
dc.identifier.doi | 10.5009/gnl16521 | - |
dc.relation.page | 852-859 | - |
dc.relation.journal | GUT AND LIVER | - |
dc.contributor.googleauthor | Jeong, Jae Yoon | - |
dc.contributor.googleauthor | Sohn, Joo Hyun | - |
dc.contributor.googleauthor | Sohn, Won | - |
dc.contributor.googleauthor | Park, Chan Hyuk | - |
dc.contributor.googleauthor | Kim, Tae Yeob | - |
dc.contributor.googleauthor | Jun, Dae Won | - |
dc.contributor.googleauthor | Kim, Yongsoo | - |
dc.contributor.googleauthor | Jeong, Woo Kyoung | - |
dc.relation.code | 2017005721 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF MEDICINE[S] | - |
dc.sector.department | DEPARTMENT OF MEDICINE | - |
dc.identifier.pid | noshin | - |
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