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Association between nocturnal blood pressure variation and wake-up ischemic stroke

Title
Association between nocturnal blood pressure variation and wake-up ischemic stroke
Author
고성호
Keywords
Wake-up stroke; Ambulatory blood pressure monitoring; Nocturnal dipping; Morning surge; Metabolic syndrome; Ischemic stroke
Issue Date
2017-10
Publisher
ELSEVIER SCI LTD
Citation
JOURNAL OF CLINICAL NEUROSCIENCE, v. 44, page. 210-213
Abstract
Ischemic stroke during nocturnal sleep, known as wake-up stroke (WUS), has been reported to have more severe symptoms and worse outcomes than non-WUS. However, studies on risk factors for WUS are scarce and the association between nocturnal blood pressure (BP) and WUS is unclear. In this study, we used ambulatory blood pressure monitoring (ABPM) to examine the association between WUS and variation in nocturnal BP. A total of 369 patients with ischemic stroke within one week were consecutively enrolled. ABPM was applied 1-2 weeks after the ictus because of possible reactive increments of BP; antihypertensive medications were delayed until ABPM. Patients were classified into two groups: WUS and non-WUS. Clinical characteristics, including ABPM parameters, were compared. Sixty-seven (18%) patients had WUS. In univariate analysis, patients with WUS had more severe stroke symptoms than patients with non-WUS. There were no differences in clinical characteristics. In addition, ABPM parameters, including nocturnal BP dipping and morning BP surge, were not associated with occurrence of WUS. Patients with WUS had more severe stroke symptoms and worse outcomes than those with non-WUS. Variation in nocturnal BP may not associated with the occurrence of WUS. (C) 2017 Elsevier Ltd. All rights reserved.
URI
https://www.jocn-journal.com/article/S0967-5868(17)30730-0/fulltexthttp://repository.hanyang.ac.kr/handle/20.500.11754/115986
ISSN
0967-5868; 1532-2653
DOI
10.1016/j.jocn.2017.06.066
Appears in Collections:
COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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