12 0

한국인 뾰족콘딜로마 환자의 임상 및사람유두종바이러스 유전자형에 대한 분석

Title
한국인 뾰족콘딜로마 환자의 임상 및사람유두종바이러스 유전자형에 대한 분석
Other Titles
Clinical Manifestations and Genotypes of Human Papillomavirus in Korean Patients with Condyloma Acuminatum
Author
김정수
Keywords
Condyloma acuminatum; Human papillomavirus
Issue Date
2017-08
Publisher
대한피부과학회
Citation
대한피부과학회지, v. 55, no. 7, page. 394-400
Abstract
Background: Condyloma acuminatum is a sexually transmitted disease (STD) associated with the human papillomavirus (HPV). Although it is a relatively common disease, there has been no epidemiological and clinical study of condyloma acuminatum performed in Korea since 1978.Objective: We aimed to evaluate the clinical features of condyloma acuminatum in Korean patients, to identify the genotypes of HPV, as well as determine factors associated with recurrence of condyloma acuminatum.Methods: We studied 80 patients (60 men and 20 women) diagnosed with condyloma acuminatum. We analyzed age, sex, duration of the disease, number and locations of lesions, underlying diseases and co-infection with STDs, treatment modalities, and number of relapses. Additionally, 26 patients were analyzed for HPV subtypes. We also evaluated factors affecting recurrence of condyloma.Results: Mean age at the time of diagnosis was 36.9±17.7 years and mean duration of disease was 7.2±16.5 months. The most common sites of involvement were found to be the penile shaft in men and the labia majora in women. We observed that 28 patients showed relapse with a mean duration of 1.5±4.5 months. HPV genotyping revealed that type 6, 11, and 44 genotypes that are associated with a low risk of malignancy were detected in 76.9% of cases, and type 16, 18, 51, 52, and 66 genotypes associated with a high risk of malignancy were detected in 15.3% cases. A significant relationship was observed between the recurrence rates of condyloma acuminatum and the rates of co-infection with STDs and the number of lesions.Conclusion: We report a recent epidemiological and clinical review analyzing genotypes of HPV in Korean patients presenting with condyloma acuminatum.
URI
http://www.papersearch.net/thesis/article.asp?key=3535735http://repository.hanyang.ac.kr/handle/20.500.11754/115236
ISSN
0494-4739
Appears in Collections:
COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE