Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Ramakrishna Suresh | - |
dc.date.accessioned | 2019-11-26T04:07:59Z | - |
dc.date.available | 2019-11-26T04:07:59Z | - |
dc.date.issued | 2017-06 | - |
dc.identifier.citation | OPEN BIOLOGY, v. 7, no. 6, Article no. 170016 | en_US |
dc.identifier.issn | 2046-2441 | - |
dc.identifier.uri | https://royalsocietypublishing.org/doi/10.1098/rsob.170016 | - |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/114507 | - |
dc.description.abstract | Deubiquitylating enzymes (DUBs) reverse the ubiquitylation of target proteins, thereby regulating diverse cellular functions. In contrast to the plethora of research being conducted on the ability of DUBs to counter the degradation of cellular proteins or auto-ubiquitylated E3 ligases, very little is known about the mechanisms of DUB regulation. In this review paper, we summarize a novel possible mechanism of DUB deubiquitylation by other DUBs. The available data suggest the need for further experiments to validate and characterize this notion of 'Dubbing DUBs'. The current studies indicate that the idea of deubiquitylation of DUBs by other DUBs is still in its infancy. Nevertheless, future research holds the promise of validation of this concept. | en_US |
dc.description.sponsorship | This study was supported by a grant of the National Research Foundation of Korea (2015R1C1A1A01054482). | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | ROYAL SOC | en_US |
dc.subject | auto-regulation | en_US |
dc.subject | deubiquitylating DUBs | en_US |
dc.subject | proteasome degradation | en_US |
dc.subject | self-deubiquitylation | en_US |
dc.subject | ubiquitylation | en_US |
dc.title | Deubiquitylation of deubiquitylases | en_US |
dc.type | Article | en_US |
dc.relation.no | 6 | - |
dc.relation.volume | 7 | - |
dc.identifier.doi | 10.1098/rsob.170016 | - |
dc.relation.page | 1-11 | - |
dc.relation.journal | OPEN BIOLOGY | - |
dc.contributor.googleauthor | Haq, Saba | - |
dc.contributor.googleauthor | Ramakrishna, Suresh | - |
dc.relation.code | 2017008374 | - |
dc.sector.campus | S | - |
dc.sector.daehak | GRADUATE SCHOOL OF BIOMEDICAL SCIENCE AND ENGINEERING[S] | - |
dc.identifier.pid | suri28 | - |
dc.identifier.orcid | http://orcid.org/0000-0002-4038-1085 | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.