Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 채영규 | - |
dc.date.accessioned | 2019-11-26T01:03:35Z | - |
dc.date.available | 2019-11-26T01:03:35Z | - |
dc.date.issued | 2017-06 | - |
dc.identifier.citation | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v. 18, no. 7, Article no. 1386 | en_US |
dc.identifier.issn | 1422-0067 | - |
dc.identifier.uri | https://www.mdpi.com/1422-0067/18/7/1386 | - |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/114354 | - |
dc.description.abstract | Ethanol is well known as a teratogenic factor that is capable of inducing a wide range of developmental abnormalities if the developing fetus is exposed to it. Duration and dose are the critical parameters of exposure that affect teratogenic variation to the developing fetus. It is suggested that ethanol interferes with epigenetic processes especially DNA methylation. We aimed to organize all of the available information on the alteration of DNA methylation by ethanol in utero. Thus, we have summarized all published information regarding alcohol-mediated alterations in DNA methylation during gestation. We tried to arrange information in a way that anyone can easily find the alcohol exposure time, doses, sampling time, and major changes in genomic level. Manuscript texts will also represent the correlation between ethanol metabolites and subsequent changes in methylome patterns. We hope that this review will help future researchers to further examine the issues associated with ethanol exposure. | en_US |
dc.description.sponsorship | This work was supported by National research foundation of Korea (NRF) funded by Korean Government under grant number 2011-0030049 to Young Gyu Chai. | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | MDPI AG | en_US |
dc.subject | alcohol | en_US |
dc.subject | epigenetics | en_US |
dc.subject | DNA methylation | en_US |
dc.subject | FASD | en_US |
dc.subject | fetal development | en_US |
dc.title | Gestational Alcohol Exposure Altered DNA Methylation Status in the Developing Fetus | en_US |
dc.type | Article | en_US |
dc.relation.no | 7 | - |
dc.relation.volume | 18 | - |
dc.identifier.doi | 10.3390/ijms18071386 | - |
dc.relation.page | 1-14 | - |
dc.relation.journal | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | - |
dc.contributor.googleauthor | Mandal, Chanchal | - |
dc.contributor.googleauthor | Halder, Debasish | - |
dc.contributor.googleauthor | Jung, Kyoung Hwa | - |
dc.contributor.googleauthor | Chai, Young Gyu | - |
dc.relation.code | 2017008229 | - |
dc.sector.campus | S | - |
dc.sector.daehak | GRADUATE SCHOOL[S] | - |
dc.sector.department | DEPARTMENT OF BIONANOTECHNOLOGY | - |
dc.identifier.pid | ygchai | - |
dc.identifier.orcid | http://orcid.org/0000-0002-3333-4803 | - |
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