Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 이영복 | - |
dc.date.accessioned | 2019-11-21T04:18:03Z | - |
dc.date.available | 2019-11-21T04:18:03Z | - |
dc.date.issued | 2017-03 | - |
dc.identifier.citation | CHEMISTRY-A EUROPEAN JOURNAL, v. 23, v. 18, page. 4292-4297 | en_US |
dc.identifier.issn | 0947-6539 | - |
dc.identifier.issn | 1521-3765 | - |
dc.identifier.uri | https://onlinelibrary.wiley.com/doi/abs/10.1002/chem.201604722 | - |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/113094 | - |
dc.description.abstract | This study introduces an extremely stable attractive nanoscale emulsion fluid, in which the amphiphilic block copolymer, poly(ethylene oxide)-block-poly(e-caprolactone) (PEO-b-PCL), is tightly packed with lecithin, thereby forming a mechanically robust thin-film at the oil-water interface. The molecular association of PEO-b-PCL with lecithin is critical for formation of a tighter and denser molecular assembly at the interface, which is systematically confirmed by T-2 relaxation and DSC analyses. Moreover, suspension rheology studies also reflect the interdroplet attractions over a wide volume fraction range of the dispersed oil phase; this results in a percolated network of stable drops that exhibit no signs of coalescence or phase separation. This unique rheological behavior is attributed to the dipolar interaction between the phosphorylcholine groups of lecithin and the methoxy end groups of PEO-b-PCL. Finally, the nanoemulsion system significantly enhances transdermal delivery efficiency due to its favorable attraction to the skin, as well as high diffusivity of the nanoscale emulsion drops. | en_US |
dc.description.sponsorship | This research was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIP) (No. 2008-0061891 and No. 2016R1A2B2016148), and by the National Science Foundation (DMR-1609841). | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | WILEY-V C H VERLAG GMBH | en_US |
dc.subject | attractive nanoemulsions | en_US |
dc.subject | block copolymers | en_US |
dc.subject | drop-percolated emulsion | en_US |
dc.subject | drug delivery | en_US |
dc.subject | lecithin | en_US |
dc.title | Structurally Stable Attractive Nanoscale Emulsions with DipoleDipole Interaction- Driven Interdrop Percolation | en_US |
dc.type | Article | en_US |
dc.relation.no | 18 | - |
dc.relation.volume | 23 | - |
dc.identifier.doi | 10.1002/chem.201604722 | - |
dc.relation.page | 4292-4297 | - |
dc.relation.journal | CHEMISTRY-A EUROPEAN JOURNAL | - |
dc.contributor.googleauthor | Shin, Kyounghee | - |
dc.contributor.googleauthor | Gong, Gyeonghyeon | - |
dc.contributor.googleauthor | Cuadrado, Jonas | - |
dc.contributor.googleauthor | Jeon, Serim | - |
dc.contributor.googleauthor | Seo, Mintae | - |
dc.contributor.googleauthor | Choi, Hong Sung | - |
dc.contributor.googleauthor | Hwang, Jae Sung | - |
dc.contributor.googleauthor | Lee, Youngbok | - |
dc.contributor.googleauthor | Fernandez-Nieves, Alberto | - |
dc.contributor.googleauthor | Kim, Jin Woong | - |
dc.relation.code | 2017002597 | - |
dc.sector.campus | S | - |
dc.sector.daehak | GRADUATE SCHOOL[S] | - |
dc.sector.department | DEPARTMENT OF BIONANOTECHNOLOGY | - |
dc.identifier.pid | yblee | - |
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