3D U-Net for Skull Stripping in Brain MRI
- Title
- 3D U-Net for Skull Stripping in Brain MRI
- Author
- 이성온
- Keywords
- skull stripping; brian segmentation; brain extraction; deep convolutional neural networks; U-Net
- Issue Date
- 2019-02
- Publisher
- MDPI
- Citation
- APPLIED SCIENCES-BASEL, v. 9, No. 3, Article no. 569
- Abstract
- Skull stripping in brain magnetic resonance imaging (MRI) is an essential step to analyze images of the brain. Although manual segmentation has the highest accuracy, it is a time-consuming task. Therefore, various automatic segmentation algorithms of the brain in MRI have been devised and proposed previously. However, there is still no method that solves the entire brain extraction problem satisfactorily for diverse datasets in a generic and robust way. To address these shortcomings of existing methods, we propose the use of a 3D-UNet for skull stripping in brain MRI. The 3D-UNet was recently proposed and has been widely used for volumetric segmentation in medical images due to its outstanding performance. It is an extended version of the previously proposed 2D-UNet, which is based on a deep learning network, specifically, the convolutional neural network. We evaluated 3D-UNet skull-stripping using a publicly available brain MRI dataset and compared the results with three existing methods (BSE, ROBEX, and Kleesiek's method; BSE and ROBEX are two conventional methods, and Kleesiek's method is based on deep learning). The 3D-UNet outperforms two typical methods and shows comparable results with the specific deep learning-based algorithm, exhibiting a mean Dice coefficient of 0.9903, a sensitivity of 0.9853, and a specificity of 0.9953.
- URI
- https://www.mdpi.com/2076-3417/9/3/569https://repository.hanyang.ac.kr/handle/20.500.11754/112400
- ISSN
- 2076-3417
- DOI
- 10.3390/app9030569
- Appears in Collections:
- COLLEGE OF ENGINEERING SCIENCES[E](공학대학) > ELECTRICAL ENGINEERING(전자공학부) > Articles
- Files in This Item:
- 2019.02_이성온_3D U-Net for Skull Stripping in Brain MRI.pdfDownload
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