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dc.contributor.author성민철-
dc.date.accessioned2019-11-18T07:53:57Z-
dc.date.available2019-11-18T07:53:57Z-
dc.date.issued2017-01-
dc.identifier.citationJOURNAL OF OPHTHALMOLOGY, Article no. 8365090en_US
dc.identifier.issn2090-004X-
dc.identifier.issn2090-0058-
dc.identifier.urihttps://www.hindawi.com/journals/joph/2017/8365090/-
dc.identifier.urihttp://repository.hanyang.ac.kr/handle/20.500.11754/112212-
dc.description.abstractPurpose. To evaluate the diagnostic ability of the retinal nerve fiber layer (RNFL) deviation map for glaucoma with localized or diffuse RNFL defects. Methods. Eyes of 139 glaucoma patients and 165 healthy subjects were enrolled. All participants were imaged with Cirrus HD-OCT (Carl Zeiss Meditec, Dublin, CA, USA). A RNFL defect was defined as at least 10 contiguous red (< 1% level) superpixels in RNFL deviation map. The area, location, and angular width of RNFL defects were automatically measured. We compared sensitivities, specificities, and area under the receiver operating characteristic curves (AUCs) of RNFL deviation map and circumpapillary RNFL thickness for localized and diffuse RNFL defects. Subgroup analysis was performed according to the severity of glaucoma. Results. For localized defects, the area of RNFL defects (AUC, 0.991; sensitivity, 97%; specificity, 90%) in deviation map showed a higher diagnostic performance (p = 0.002) than the best circumpapillary RNFL parameter (inferior RNFL thickness; AUC, 0.914; sensitivity, 79%; specificity, 92%). For diffuse defects, there was no significant difference between the RNFL deviation map and circumpapillary RNFL parameters. In mild glaucoma with localized defect, RNFL deviation map showed a better diagnostic performance than circumpapillary RNFL measurement. Conclusions. RNFL deviation map is a useful tool for evaluating glaucoma regardless of localized or diffuse defect type and has advantages over circumpapillary RNFL measurement for detecting localized RNFL defects.en_US
dc.language.isoenen_US
dc.publisherHINDAWI LTDen_US
dc.subjectOPTICAL COHERENCE TOMOGRAPHYen_US
dc.subjectGLAUCOMA DIAGNOSISen_US
dc.subjectNORMATIVE DATABASEen_US
dc.subjectSTRATUS OCTen_US
dc.titleDiagnostic Ability of Retinal Nerve Fiber Layer Thickness Deviation Map for Localized and Diffuse Retinal Nerve Fiber Layer Defectsen_US
dc.typeArticleen_US
dc.identifier.doi10.1155/2017/8365090-
dc.relation.page1-9-
dc.relation.journalJOURNAL OF OPHTHALMOLOGY-
dc.contributor.googleauthorShin, Joong Won-
dc.contributor.googleauthorSeong, Mincheol-
dc.contributor.googleauthorLee, Jung Wook-
dc.contributor.googleauthorHong, Eun Hee-
dc.contributor.googleauthorUhm, Ki Bang-
dc.relation.code2017007775-
dc.sector.campusS-
dc.sector.daehakCOLLEGE OF MEDICINE[S]-
dc.sector.departmentDEPARTMENT OF MEDICINE-
dc.identifier.pidgoddns76-


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