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Fabrication and characterization of 3D scaffolds made from blends of sodium alginate and poly(vinyl alcohol)

Title
Fabrication and characterization of 3D scaffolds made from blends of sodium alginate and poly(vinyl alcohol)
Author
신흥수
Keywords
3D printing; Lyophilization; Sodium alginate; Poly (vinyl alcohol); Porosity; Scaffold
Issue Date
2019-06
Publisher
ELSEVIER SCIENCE BV
Citation
MATERIALS TODAY COMMUNICATIONS, v. 19, Page. 56-61
Abstract
Sodium alginate (SA) is a non-toxic, biocompatible and biodegradable natural polymer. It has good printability, which is why it is often used in inks for three-dimensional (3D) printing in tissue engineering fields. However, pure SA hydrogel has unstable mechanical properties. In this study, we fabricated a structurally stable 3D scaffold by blending SA with poly(vinyl alcohol) (PVA) to enhance the mechanical properties of the scaffold. Moreover, we characterized the surface morphology and various mechanical properties of the scaffolds using scanning electron microscopy, Fourier transform-infrared spectroscopy, thermogravimetric analysis and several mechanical tests. The SA/PVA scaffolds were mechanically more stable than the pure SA scaffold and are good candidate as implantable biodegradable scaffolds for tissue engineering and medical applications.
URI
https://www.sciencedirect.com/science/article/pii/S2352492818301922?via%3Dihubhttp://repository.hanyang.ac.kr/handle/20.500.11754/111850
ISSN
2352-4928
DOI
10.1016/j.mtcomm.2018.09.013
Appears in Collections:
COLLEGE OF ENGINEERING[S](공과대학) > BIOENGINEERING(생명공학과) > Articles
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