Estrogenic activity of furanocoumarins isolated from Angelica dahurica
- Title
- Estrogenic activity of furanocoumarins isolated from Angelica dahurica
- Author
- 유혜현
- Keywords
- Angelica dahurica; Umbelliferae; furanocoumarin; estrogenic activity
- Issue Date
- 2006-09
- Publisher
- PHARMACEUTICAL SOCIETY KOREA
- Citation
- ARCHIVES OF PHARMACAL RESEARCH, v. 29, No. 9, Page. 741-745
- Abstract
- In our efforts to discover novel phytoestrogens to treat menopausal symptoms, eleven furanocoumarins were isolated from Angelica dahurica and tested for their estrogenic activity on the Ishikawa cell line. Among the compounds tested, 9-hydroxy-4-methoxypsoralen and alloisoimperatorin showed strong abilities to induce alkaline phosphatase (AP) with EC50 values of 1.1 and 0.8 mu g/mL, respectively, whereas the other nine furanocoumarins were weakly or only slightly active.
- URI
- https://link.springer.com/article/10.1007/BF02974073https://repository.hanyang.ac.kr/handle/20.500.11754/108514
- ISSN
- 0253-6269; 1976-3786
- DOI
- 10.1007/BF02974073
- Appears in Collections:
- COLLEGE OF PHARMACY[E](약학대학) > PHARMACY(약학과) > Articles
- Files in This Item:
There are no files associated with this item.
- Export
- RIS (EndNote)
- XLS (Excel)
- XML