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dc.contributor.author황승용-
dc.date.accessioned2019-07-26T01:30:32Z-
dc.date.available2019-07-26T01:30:32Z-
dc.date.issued2019-01-
dc.identifier.citationMOLECULAR & CELLULAR TOXICOLOGY, v. 15, NO 1, Page. 1-7en_US
dc.identifier.issn1738-642X-
dc.identifier.issn2092-8467-
dc.identifier.urihttps://link.springer.com/article/10.1007%2Fs13273-019-0001-4-
dc.identifier.urihttp://repository.hanyang.ac.kr/handle/20.500.11754/107906-
dc.description.abstractPurpose of reviewExposure to toxic substances from different environmental sources has an enormous impact on the public health, and is considered to be an important social issue. Therefore, omics approaches are used to understand relationships between diseases and environmental factors, but single omics analysis may have limitations in comprehensively interpreting specific biological phenomena. Multi-omics approaches, on the other hand, combines various single omics analyses in order to understand holistic biological mechanisms, which is sequentially assessed starting at the DNA sequence level and proceeding through epigenetic regulation, gene expression, protein expression and metabolic effects.Recent findingsIntegration of multiple omics data is invaluable for comprehensively understanding causal relationship between environmental exposure and environmental health. Furthermore, cohort based multi-omics studies are in activation worldwide and the approaches could strengthen comprehension on how environmental factors affects human health by alteration of molecular-level of biological mechanisms.en_US
dc.description.sponsorshipThis study was supported by Korea Environment Industry & Technology Institute (KEITI) through "the Environmental Health Action Program", funded by Korea Ministry of Environment (MOE) (2017 001360005).en_US
dc.language.isoenen_US
dc.publisherSPRINGERen_US
dc.subjectMulti-omicsen_US
dc.subjectIntegrated analysisen_US
dc.subjectNext Generation Sequencing (NGS)en_US
dc.subjectEnvironmental exposureen_US
dc.subjectEnvironmental healthen_US
dc.subjectRisk assessmenten_US
dc.titleMulti-omics approaches for understanding environmental exposure and human healthen_US
dc.typeArticleen_US
dc.relation.no1-
dc.relation.volume15-
dc.identifier.doi10.1007/s13273-019-0001-4-
dc.relation.page1-7-
dc.relation.journalMOLECULAR & CELLULAR TOXICOLOGY-
dc.contributor.googleauthorKoh, Eun Jung-
dc.contributor.googleauthorHwang, Seung Yong-
dc.relation.code2019043645-
dc.sector.campusS-
dc.sector.daehakGRADUATE SCHOOL[S]-
dc.sector.departmentDEPARTMENT OF BIONANOTECHNOLOGY-
dc.identifier.pidsyhwang-
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GRADUATE SCHOOL[S](대학원) > BIONANOTECHNOLOGY(바이오나노학과) > Articles
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