6 0

Multi-omics approaches for understanding environmental exposure and human health

Title
Multi-omics approaches for understanding environmental exposure and human health
Author
황승용
Keywords
Multi-omics; Integrated analysis; Next Generation Sequencing (NGS); Environmental exposure; Environmental health; Risk assessment
Issue Date
2019-01
Publisher
SPRINGER
Citation
MOLECULAR & CELLULAR TOXICOLOGY, v. 15, NO 1, Page. 1-7
Abstract
Purpose of reviewExposure to toxic substances from different environmental sources has an enormous impact on the public health, and is considered to be an important social issue. Therefore, omics approaches are used to understand relationships between diseases and environmental factors, but single omics analysis may have limitations in comprehensively interpreting specific biological phenomena. Multi-omics approaches, on the other hand, combines various single omics analyses in order to understand holistic biological mechanisms, which is sequentially assessed starting at the DNA sequence level and proceeding through epigenetic regulation, gene expression, protein expression and metabolic effects.Recent findingsIntegration of multiple omics data is invaluable for comprehensively understanding causal relationship between environmental exposure and environmental health. Furthermore, cohort based multi-omics studies are in activation worldwide and the approaches could strengthen comprehension on how environmental factors affects human health by alteration of molecular-level of biological mechanisms.
URI
https://link.springer.com/article/10.1007%2Fs13273-019-0001-4http://repository.hanyang.ac.kr/handle/20.500.11754/107906
ISSN
1738-642X; 2092-8467
DOI
10.1007/s13273-019-0001-4
Appears in Collections:
GRADUATE SCHOOL[S](대학원) > BIONANOTECHNOLOGY(바이오나노학과) > Articles
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE