Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김경수 | - |
dc.date.accessioned | 2019-05-27T05:53:37Z | - |
dc.date.available | 2019-05-27T05:53:37Z | - |
dc.date.issued | 2015-03 | - |
dc.identifier.citation | DRUG DEVELOPMENT RESEARCH, v. 76, No. 3, Page. 157-165 | en_US |
dc.identifier.issn | 0272-4391 | - |
dc.identifier.issn | 1098-2299 | - |
dc.identifier.uri | https://onlinelibrary.wiley.com/doi/full/10.1002/ddr.21253 | - |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/106011 | - |
dc.description.abstract | The purpose of this study was to evaluate the wound-healing effects of a novel benzalkonium chloride (BC)-loaded hydrocolloid wound dressing (HCD). A BC-loaded HCD was prepared with various constituents using a hot melting method, and its mechanical properties and antimicrobial activities were assessed. The in vivo wound healings of the BC-loaded HCD in various would models were evaluated in rats compared with a commercial wound dressing, Duoderm. This BC-loaded HCD gave better skin adhesion, swelling, mechanical strength, and flexibility compared with the commercial wound dressing. It showed excellent antimicrobial activity against Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa. In addition, as compared with the commercial wound dressing, it showed more improved wound healings and tissue restoration effect on the excision, infection, and abrasion wounds in rats. Thus, this novel BC-loaded HCD would be an excellent alternative to the commercial wound dressing for treatment of various wounds. | en_US |
dc.description.sponsorship | This work was supported by the National Research Foundation of South Korea (NRF) grant funded by the South Korea government (MEST) (No. 2012R1A2A2A01045658). | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | WILEY-BLACKWELL | en_US |
dc.subject | benzalkonium chloride | en_US |
dc.subject | wound dressing | en_US |
dc.subject | wound healing | en_US |
dc.subject | abrasion wound | en_US |
dc.subject | excision wound | en_US |
dc.subject | infection wound | en_US |
dc.title | In Vivo Wound-Healing Effects of Novel Benzalkonium Chloride-Loaded Hydrocolloid Wound Dressing | en_US |
dc.type | Article | en_US |
dc.relation.no | 3 | - |
dc.relation.volume | 76 | - |
dc.identifier.doi | 10.1002/ddr.21253 | - |
dc.relation.page | 157-165 | - |
dc.relation.journal | DRUG DEVELOPMENT RESEARCH | - |
dc.contributor.googleauthor | Jin, Sung Giu | - |
dc.contributor.googleauthor | Yousaf, Abid Mehmood | - |
dc.contributor.googleauthor | Jang, Sun Woo | - |
dc.contributor.googleauthor | Son, Mi-Won | - |
dc.contributor.googleauthor | Kim, Kyung Soo | - |
dc.contributor.googleauthor | Kim, Dong-Wuk | - |
dc.contributor.googleauthor | Li, Dong Xun | - |
dc.contributor.googleauthor | Kim, Jong Oh | - |
dc.contributor.googleauthor | Yong, Chul Soon | - |
dc.contributor.googleauthor | Choi, Han-Gon | - |
dc.relation.code | 2015002873 | - |
dc.sector.campus | E | - |
dc.sector.daehak | RESEARCH INSTITUTE[E] | - |
dc.sector.department | INSTITUTE OF PHARMACEUTICAL SCIENCE AND TECHNOLOGY | - |
dc.identifier.pid | soyo79 | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.