Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김은진 | - |
dc.date.accessioned | 2019-05-23T04:51:47Z | - |
dc.date.available | 2019-05-23T04:51:47Z | - |
dc.date.issued | 2015-08 | - |
dc.identifier.citation | TRENDS IN MICROBIOLOGY, v. 23, No. 8, Page. 479-489 | en_US |
dc.identifier.issn | 0966-842X | - |
dc.identifier.issn | 1878-4380 | - |
dc.identifier.uri | https://www.sciencedirect.com/science/article/pii/S0966842X15000773 | - |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/105911 | - |
dc.description.abstract | The analysis of the whole-genome sequences of Vibrio cholerae strains from previous and current cholera pandemics has demonstrated that genomic changes and alterations in phage CTX (particularly in the gene encoding the B subunit of cholera toxin) were major features in the evolution of V. cholerae. Recent studies have revealed the genetic mechanisms in these bacteria by which new variants of V. cholerae are generated from type-specific strains; these mechanisms suggest that certain strains are selected by environmental or human factors over time. By understanding the mechanisms and driving forces of historical and current changes in the V. cholerae population, it would be possible to predict the direction of such changes and the evolution of new variants; this has implications for the battle against cholera. | en_US |
dc.description.sponsorship | This work was supported by grant 2012R1A2A2A01009741 from the National Research Foundation (NRF) of Korea. | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | ELSEVIER SCI LTD | en_US |
dc.subject | Vibrio cholerae | en_US |
dc.subject | cholera | en_US |
dc.subject | cholera toxin | en_US |
dc.subject | phage CTX | en_US |
dc.title | Whole-genome sequence comparisons reveal the evolution of Vibrio cholerae O1 | en_US |
dc.type | Article | en_US |
dc.relation.no | 8 | - |
dc.relation.volume | 23 | - |
dc.identifier.doi | 10.1016/j.tim.2015.03.010 | - |
dc.relation.page | 479-489 | - |
dc.relation.journal | TRENDS IN MICROBIOLOGY | - |
dc.contributor.googleauthor | Kim, Eun Jin | - |
dc.contributor.googleauthor | Lee, Chan Hee | - |
dc.contributor.googleauthor | Nair, G. Balakrish | - |
dc.contributor.googleauthor | Kim, Dong Wook | - |
dc.relation.code | 2015001986 | - |
dc.sector.campus | E | - |
dc.sector.daehak | INDUSTRY-UNIVERSITY COOPERATION FOUNDATION(ERICA)[E] | - |
dc.sector.department | RESEARCH INSTITUTE | - |
dc.identifier.pid | ejkim0816 | - |
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