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Four New Acylated Iridoid Glycosides from the Aerial Part of Veronicastrum sibiricum and Their Antioxidant Response Element-Inducing Activity

Title
Four New Acylated Iridoid Glycosides from the Aerial Part of Veronicastrum sibiricum and Their Antioxidant Response Element-Inducing Activity
Author
김철영
Keywords
Veronicastrum sibiricum (L; ); Pennell; Scrophulariaceae; acylated iridoid glycosides; antioxidant response element; ARE-luciferase reporter assay
Issue Date
2018-01
Publisher
WILEY-V C H VERLAG GMBH
Citation
CHEMISTRY & BIODIVERSITY, v. 15, No. 1, Article no. e1700447
Abstract
Four new (1 - 4) and one known (5) acylated iridoid glycosides were isolated from the aerial parts of Veronicastrum sibiricum (L.) Pennell. The chemical structures of the isolated compounds were determined to be 3,4-dicinnamoyl-6-O-rhamnopyranosyl-10-O-bergaptol-5,7-bisdeoxycynanchoside (1), 3,4-dicinnamoyl-6-O-rhamnopyranosylpaulownioside (2), 2,4-dicinnamoyl-6-O-rhamnopyranosylcatalpol (3), 3,4-dicinnamoyl-6-O-rhamnopyranosylaucubin (4), and 3,4-dicinnamoyl-6-O-rhamnopyranosylcatalpol (5) using spectroscopic techniques. Among these compounds, compound 5 increased antioxidant response element (ARE) luciferase activity.
URI
https://onlinelibrary.wiley.com/doi/abs/10.1002/cbdv.201700447http://repository.hanyang.ac.kr/handle/20.500.11754/105317
ISSN
1612-1872
DOI
10.1002/cbdv.201700447
Appears in Collections:
COLLEGE OF PHARMACY[E](약학대학) > PHARMACY(약학과) > Articles
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