Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 유혜현 | - |
dc.date.accessioned | 2019-05-22T00:48:45Z | - |
dc.date.available | 2019-05-22T00:48:45Z | - |
dc.date.issued | 2008-12 | - |
dc.identifier.citation | JOURNAL OF AOAC INTERNATIONAL, v. 91, No. 6, Page. 1271-1277 | en_US |
dc.identifier.issn | 1060-3271 | - |
dc.identifier.uri | https://www.ingentaconnect.com/content/aoac/jaoac/2008/00000091/00000006/art00004 | - |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/105275 | - |
dc.description.abstract | The rhizomes of Anemarrhena asphodeloides Bunge (Liliaceae) are prescribed as crude drugs in herbal medication for the treatment of various diseases such as diabetes, inflammation, and platelet aggregation inhibition. A simple, sensitive, and precise reversed-phase liquid chromatographic method was developed to study the quantitative determination of 5 bioactive compounds from these rhizomes, namely, neomangiferin, mangiferin, isomangiferin, nyasol, and methylnyasol. Chromatographic analysis was performed on Capcell Pak C-18 column (150 x 4.6 mm, 3 mu m) with a mobile phase consisting of acetonitrile, methanol, and 0.1% formic acid at a flow rate of 1.00 mL/min. Quantitation was performed using a UV-visible detector at 260 nm. The method for the determination of reported medicinal agents was accurate and reproducible. Excellent linear behavior was observed over the investigated concentration range of 2.5-100.0 mu g/mL for neomangiferin; 1.5-60.0 mu g/mL for mangiferin; 0.5-20.0 mu g/mL for nyasol; and 0.2-20.0 mu g/mL for methylnyasol; correlation coefficient > 0.99. The intraday and interday precision over the concentration range of compounds was < 6.6% (relative standard deviation) and accuracy was between 94.9 and 109.3%. This method can be successfully applied for the analysis of medicinal compounds from the ethanolic extract of A. asphodeloides Bunge. | en_US |
dc.description.sponsorship | This work was supported in part by grants from Korea Food and Drug Administration and by Seoul Research and Business Development Program. | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | AOAC INTERNATIONAL | en_US |
dc.subject | TANDEM MASS-SPECTROMETRY | en_US |
dc.subject | SWERTIA-MUSSOTII FRANCH | en_US |
dc.subject | RAT PLASMA | en_US |
dc.subject | CAPILLARY-ELECTROPHORESIS | en_US |
dc.subject | ANTIDIABETIC ACTIVITY | en_US |
dc.subject | ANTIOXIDANT ACTIVITY | en_US |
dc.subject | ACTIVE CONSTITUENTS | en_US |
dc.subject | MANGIFERIN | en_US |
dc.subject | IDENTIFICATION | en_US |
dc.subject | RHIZOMES | en_US |
dc.title | Simultaneous Determination of Bioactive Xanthone Glycosides and Norlignans from Ethanolic Extract of Anemarrhena asphodeloides by Liquid Chromatography | en_US |
dc.type | Article | en_US |
dc.relation.volume | 91 | - |
dc.relation.page | 1271-1277 | - |
dc.relation.journal | JOURNAL OF AOAC INTERNATIONAL | - |
dc.contributor.googleauthor | Islam, M. Nurul | - |
dc.contributor.googleauthor | Yoo, Hye Hyun | - |
dc.contributor.googleauthor | Lee, Jun | - |
dc.contributor.googleauthor | Nam, Joo Won | - |
dc.contributor.googleauthor | Seo, Eun Kyoung | - |
dc.contributor.googleauthor | Jin, Changbae | - |
dc.contributor.googleauthor | Kim, Dong-Hyun | - |
dc.relation.code | 2008204643 | - |
dc.sector.campus | E | - |
dc.sector.daehak | COLLEGE OF PHARMACY[E] | - |
dc.sector.department | DEPARTMENT OF PHARMACY | - |
dc.identifier.pid | yoohh | - |
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