Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 조용우 | - |
dc.date.accessioned | 2019-05-20T07:25:52Z | - |
dc.date.available | 2019-05-20T07:25:52Z | - |
dc.date.issued | 2008-10 | - |
dc.identifier.citation | JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY, v. 8, No. 10, Page. 5139-5142 | en_US |
dc.identifier.issn | 1533-4880 | - |
dc.identifier.uri | https://www.ingentaconnect.com/content/asp/jnn/2008/00000008/00000010/art00047 | - |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/104994 | - |
dc.description.abstract | Terazocin should be frequently administered for a long period time for the treatment of benign prostatic hyperplasia which is one of the most common diseases in elderly men. Controlled delivery of terazocin using polymer microspheres has a great potential to solve the problem. In this study, terazocin-incorporated poly(D,L-lactide) (PDLLA) microspheres were fabricated by a novel ultrasonic spray drying (USD) method, which is a rapid one-step process. The approximate diameters of microspheres were in a range of between 0.3 and 3 mu m. SEM confirmed that the microspheres had a spherical shape and narrow size distribution. FT-IR spectroscopy demonstrated that the incorporated terazocin remained intact after the USD process. The microspheres showed a fast initial burst release of terazocin within nine hours, followed by a slow but steady release for 49 days, suggesting that these microspheres are highly promising for controlled drug delivery. | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | AMER SCIENTIFIC PUBLISHERS | en_US |
dc.subject | Utrasonic Spray Drying | en_US |
dc.subject | Microspheres | en_US |
dc.subject | Drug Delivery System | en_US |
dc.subject | Terazocin | en_US |
dc.subject | Poly(D,L-lactide) | en_US |
dc.title | Fabrication of terazocin-loaded poly(D,L-lactide) microspheres by an ultrasonic spray drying method and their release behaviors | en_US |
dc.type | Article | en_US |
dc.identifier.doi | 10.1166/jnn.2008.1138 | - |
dc.relation.journal | JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY | - |
dc.contributor.googleauthor | An, Guk-Hwan | - |
dc.contributor.googleauthor | Kim, Min-Jung | - |
dc.contributor.googleauthor | Lee, Hak-Jong | - |
dc.contributor.googleauthor | Park, Sang-Soo | - |
dc.contributor.googleauthor | Cho, Yong Woo | - |
dc.contributor.googleauthor | Park, Kinam | - |
dc.contributor.googleauthor | Choa, Yong-Ho | - |
dc.relation.code | 2008214452 | - |
dc.sector.campus | E | - |
dc.sector.daehak | COLLEGE OF ENGINEERING SCIENCES[E] | - |
dc.sector.department | DEPARTMENT OF MATERIALS SCIENCE AND CHEMICAL ENGINEERING | - |
dc.identifier.pid | ywcho7 | - |
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