33 0

Characterization of protein expression in the head of Oryzias latipes in response to acute and chronic exposure to benzo(a)pyrene

Title
Characterization of protein expression in the head of Oryzias latipes in response to acute and chronic exposure to benzo(a)pyrene
Author
문효방
Keywords
Japanese medaka; benzo(a)pyrene; proteome; environmental pollution
Issue Date
2008-10
Publisher
한국환경생물학회
Citation
환경생물, v. 26, No. 3, Page. 220-225
Abstract
In this study, alterations in whole proteome expression patterns in the head of Japanesemedaka (Oryzias latipes) was investigated following acute or chronic exposure to benzo(a)pyrene (BaP) (25 μg L-1) for 48 hrs and 15 days, respectively. The results showed that 9 and 6protein spots were statistically different, relative to controls, in response to acute and chronic BaPexposure, respectively. In the acute exposure group, 5 spots were upregulated and 4 spots weredownregulated, while in the chronic exposure group, 4 spots were upregulated and 2 spots weredownregulated. Three of these spots were common to both the acute and chronic BaP exposuregroups and were identified using LC-MS/MS followed by database searching. These 3 spots werefound to be associated with structural proteins belonging to the actin and keratin families. Thesedata suggest that acute and chronic exposures to BaP may affect tissue morphology in the head ofJapanese medaka.
URI
https://www.kci.go.kr/kciportal/ci/sereArticleSearch/ciSereArtiView.kci?sereArticleSearchBean.artiId=ART001283779http://repository.hanyang.ac.kr/handle/20.500.11754/104967
ISSN
2287-7851
Appears in Collections:
COLLEGE OF SCIENCE AND CONVERGENCE TECHNOLOGY[E](과학기술융합대학) > MARINE SCIENCE AND CONVERGENCE ENGINEERING(해양융합공학과) > Articles
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE