Full metadata record

DC FieldValueLanguage
dc.contributor.author이상열-
dc.date.accessioned2019-04-16T07:09:02Z-
dc.date.available2019-04-16T07:09:02Z-
dc.date.issued2016-02-
dc.identifier.citationJOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, v. 31, No. 1, Page. 1-13en_US
dc.identifier.issn1475-6366-
dc.identifier.issn1475-6374-
dc.identifier.urihttps://www.tandfonline.com/doi/abs/10.3109/14756366.2015.1004058-
dc.identifier.urihttp://repository.hanyang.ac.kr/handle/20.500.11754/102120-
dc.description.abstractTyrosinase plays a pivotal role in the synthesis of melanin pigment synthesis on skin utilizing tyrosine as a substrate. Melanin is responsible for the protection against harmful ultraviolet irradiation, which can cause significant pathological conditions, such as skin cancers. However, it can also create esthetic problems when accumulated as hyperpigmented spots. Various skin-whitening ingredients which inhibit tyrosinase activity have been identified. Some of them, especially ones with natural product origins, possess phenolic moiety and have been employed in cosmetic products. Semi-synthetic and synthetic inhibitors have also been developed under inspiration of the natural inhibitors yet some of which have no phenolic groups. In this review, tyrosinase inhibitors with natural, semi-synthetic and synthetic origins are listed up with their structures, activities and characteristics. Further, a recent report on the adverse effect of a natural melanin synthesis inhibitor which was included in skin-whitening cosmetics is also briefly discussed.en_US
dc.description.sponsorshipThis work was supported by Research Fund of Hanyang University (HY-2012-N).en_US
dc.language.isoen_USen_US
dc.publisherTAYLOR & FRANCIS LTDen_US
dc.subjectInhibitoren_US
dc.subjectmelaninen_US
dc.subjectskin-whiteningen_US
dc.subjecttyrosinaseen_US
dc.titleNatural, semisynthetic and synthetic tyrosinase inhibitorsen_US
dc.typeArticleen_US
dc.identifier.doi10.3109/14756366.2015.1004058-
dc.relation.page1-13-
dc.relation.journalJOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY-
dc.contributor.googleauthorLee, Sang Yeul-
dc.contributor.googleauthorBaek, Namhuk-
dc.contributor.googleauthorNam, Tae-gyu-
dc.relation.code2016002458-
dc.sector.campusE-
dc.sector.daehakRESEARCH INSTITUTE[E]-
dc.sector.departmentINSTITUTE OF PHARMACEUTICAL SCIENCE AND TECHNOLOGY-
dc.identifier.pidlsyeul2-
Appears in Collections:
RESEARCH INSTITUTE[E](부설연구소) > INSTITUTE OF PHARMACEUTICAL SCIENCE AND TECHNOLOGY(약학기술연구소) > Articles
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE