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Current Opinion on the Role of Neurogenesis in the Therapeutic Strategies for Alzheimer Disease, Parkinson Disease, and Ischemic Stroke; Considering Neuronal Voiding Function

Title
Current Opinion on the Role of Neurogenesis in the Therapeutic Strategies for Alzheimer Disease, Parkinson Disease, and Ischemic Stroke; Considering Neuronal Voiding Function
Author
고성호
Keywords
Alzheimer Disease; Parkinson Disease; Stroke; Neurogenesis; Neural Stem Cells
Issue Date
2016-12
Publisher
KOREAN CONTINENCE SOC
Citation
INTERNATIONAL NEUROUROLOGY JOURNAL, v. 20, Issue 4, Page. 276-287
Abstract
Neurological diseases such as Alzheimer, Parkinson, and ischemic stroke have increased in occurrence and become important health issues throughout the world. There is currently no effective therapeutic strategy for addressing neurological deficits after the development of these major neurological disorders. In recent years, it has become accepted that adult neural stem cells located in the subventricular and subgranular zones have the ability to proliferate and differentiate in order to replace lost or damaged neural cells. There have been many limitations in the clinical application of both endogenous and exogenous neuro-genesis for neurological disorders. However, many studies have investigated novel mechanisms in neurogenesis and have shown that these limitations can potentially be overcome with appropriate stimulation and various approaches. We will review concepts related to possible therapeutic strategies focused on the perspective of neurogenesis for the treatment of patients diagnosed with Alzheimer disease, Parkinson disease, and ischemic stroke based on current reports.
URI
https://www.einj.org/journal/view.php?doi=10.5213/inj.1632776.388http://repository.hanyang.ac.kr/handle/20.500.11754/101566
ISSN
2093-4777; 2093-6931
DOI
10.5213/inj.1632776.388
Appears in Collections:
COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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