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Simultaneous quantitation of six major quassinoids in Tongkat Ali dietary supplements by liquid chromatography with tandem mass spectrometry

Title
Simultaneous quantitation of six major quassinoids in Tongkat Ali dietary supplements by liquid chromatography with tandem mass spectrometry
Author
유혜현
Keywords
Dietary supplements; Eurycoma longifolia; Liquid chromatography with tandem mass spectrometry; Quassinoids; Tongkat Ali; EURYCOMA-LONGIFOLIA JACK; ANTIMALARIAL CONSTITUENTS; MALE-RATS; ROOTS
Issue Date
2015-07
Publisher
WILEY-V C H VERLAG GMBH
Citation
JOURNAL OF SEPARATION SCIENCE, v. 38, No. 13, Page. 2260-2266
Abstract
Tongkat Ali (Eurycoma longifolia) is one of the most popular traditional herbs in Southeast Asia and generally consumed as forms of dietary supplements, tea, or drink additives for coffee or energy beverages. In this study, the liquid chromatography with tandem mass spectrometry method for the simultaneous quantitation of six major quassinoids of Tongkat Ali (eurycomanone, 13,21-dihydroeurycomanone, 13 alpha (21)-epoxyeurycomanone, 14,15 beta-dihydroxyklaineanone, eurycomalactone, and longilactone) was developed and validated. Using the developed method, the content of the six quassinoids was measured in Tongkat Ali containing dietary supplement tablets or capsules, and the resulting data were used to confirm the presence of Tongkat Ali in those products. Among the six quassinoids, eurycomanone was the most abundant quassinoid in all samples tested. The developed method would be useful for the quality assessment of Tongkat Ali containing dietary supplements.
URI
http://onlinelibrary.wiley.com/doi/10.1002/jssc.201500207/fullhttp://repository.hanyang.ac.kr/handle/20.500.11754/101285
ISSN
1615-9306; 1615-9314
DOI
10.1002/jssc.201500207
Appears in Collections:
COLLEGE OF PHARMACY[E](약학대학) > PHARMACY(약학과) > Articles
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