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Application of MoS2 modified screen-printed electrodes for highly sensitive detection of bovine serum albumin

Title
Application of MoS2 modified screen-printed electrodes for highly sensitive detection of bovine serum albumin
Author
김기현
Keywords
MoS2; Immunosensing; Bovine serum albumin; Cyclic voltammetry
Issue Date
2016-10
Publisher
ELSEVIER SCIENCE BV
Citation
ANALYTICA CHIMICA ACTA, v. 939, Page. 101-107
Abstract
The present work reports the application of a new molybdenum disulphide (MoS2)-based electrochemical platform for highly sensitive quantitation of an iron-binding protein, bovine serum albumin (BSA). The gold screen-printed electrodes were modified with MoS2 nanoflakes, followed by bio-conjugation with anti-BSA antibodies. Using the above bioelectrode, cyclic voltammetric analysis was carried out in the presence of a Fe3+/Fe2+ redox probe which exhibited a linear response of peak current with varying concentrations of BSA up to 10 ng/mL (with a detection limit of 0.006 ng/mL). This study is novel in that it shows a considerable enhancement of signal during electrochemical sensing of a protein. (C) 2016 Elsevier B.V. All rights reserved.
URI
https://www.sciencedirect.com/science/article/pii/S0003267016309151?via%3Dihubhttp://repository.hanyang.ac.kr/handle/20.500.11754/100658
ISSN
0003-2670; 1873-4324
DOI
10.1016/j.aca.2016.08.010
Appears in Collections:
COLLEGE OF ENGINEERING[S](공과대학) > CIVIL AND ENVIRONMENTAL ENGINEERING(건설환경공학과) > Articles
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