TY - JOUR AU - 김정은 DA - 2014/06 PY - 2014 UR - http://kiss.kstudy.com/thesis/thesis-view.asp?key=3246677 UR - http://hdl.handle.net/20.500.11754/47849 AB - Department of Dermatology, Hanyang University College of Medicine, Seoul, Korea Background: Autoimmune blistering skin diseases such as pemphigus vulgaris, pemphigus foliaceus, bullous pemphigoid and epidermolysis bullosa acquisita substantially affect patients. daily life and psychosocial well-being. Objective: The aim of this study was to evaluate the quality of life (QOL) in patients with autoimmune blistering diseases and to identify the factors that can influence their QOL by comparing them to healthy controls. Methods: Forty patients with autoimmune blistering skin diseases and 40 healthy controls were interviewed using the Korean version of Skindex-29. The study assessed the clinical severity of the disease. Results: The total, symptom, function, and emotion scores of Skindex-29 were significantly higher in patients with autoimmune blistering skin diseases (35.28, 40.78, 30.57, and 36.67, respectively) than in the healthy controls (6.90, 9.38, 5.47, and 6.60, respectively) (p<0.001). Higher disease severity had a negative correlation with QOL in patients with blistering skin diseases, and QOL was lower when patients had low levels of satisfaction with treatment. Conclusion: The results show that autoimmune blistering skin diseases can affect patients’ QOL. In addition, disease severity and low satisfaction with treatment are important factors that reduce QOL. Development of new treatments should improve treatment efficacy and the QOL of patients with autoimmune blistering diseases. (Korean J Dermatol 2014;52(6):402∼409) PB - 대한피부과학회 KW - Autoimmune KW - Bullous dermatoses KW - Quality of life(QOL) KW - Skindex-29 KW - Autoimmune blistering diseases TI - 자가면역 물집 피부질환 환자의 삶의 질 IS - 6 VL - 52 T2 - 대한피부과학회지 ER -